The links below are to publications on PubMed referring to BluePyOpt. This list is gathered weekly from PubMed automatically and was last updated on December 17, 2025.

Publication/References
Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits.
Description: Yao, Heng Kang, et al. Reduced inhibition in depression impairs stimulus processing in human cortical microcircuits. ''Cell Rep''. 2022 Jan 11; '''38''' (2):110232
Multi-modal characterization and simulation of human epileptic circuitry.
Description: Buchin, Anatoly, et al. Multi-modal characterization and simulation of human epileptic circuitry. ''Cell Rep''. 2022 Dec 27; '''41''' (13):111873
Altered synaptic plasticity at hippocampal CA1-CA3 synapses in Alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models.
Description: Dainauskas, Justinas J, et al. Altered synaptic plasticity at hippocampal CA1-CA3 synapses in Alzheimer's disease: integration of amyloid precursor protein intracellular domain and amyloid beta effects into computational models. ''Front Comput Neurosci''. 2023; '''17''': 1305169
Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex.
Description: Hunt, Sarah, et al. Strong and reliable synaptic communication between pyramidal neurons in adult human cerebral cortex. ''Cereb Cortex''. 2023 Mar 10; '''33''' (6):2857-2878
Modeling Synaptic Integration of Bursty and beta Oscillatory Inputs in Ventromedial Motor Thalamic Neurons in Normal and Parkinsonian States.
Description: Cavarretta, Francesco, et al. Modeling Synaptic Integration of Bursty and beta Oscillatory Inputs in Ventromedial Motor Thalamic Neurons in Normal and Parkinsonian States. ''eNeuro''. 2023 Dec; '''10''' (12):
Human Purkinje cells outperform mouse Purkinje cells in dendritic complexity and computational capacity.
Description: Masoli, Stefano, et al. Human Purkinje cells outperform mouse Purkinje cells in dendritic complexity and computational capacity. ''Commun Biol''. 2024 Jan 2; '''7''' (1):5
A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction.
Description: Clatot, Jerome, et al. A structurally precise mechanism links an epilepsy-associated KCNC2 potassium channel mutation to interneuron dysfunction. ''Proc Natl Acad Sci U S A''. 2024 Jan 16; '''121''' (3):e2307776121
Community-based reconstruction and simulation of a full-scale model of the rat hippocampus CA1 region.
Description: Romani, Armando, et al. Community-based reconstruction and simulation of a full-scale model of the rat hippocampus CA1 region. ''PLoS Biol''. 2024 Nov; '''22''' (11):e3002861
Evaluation and comparison of methods for neuronal parameter optimization using the Neuroptimus software framework.
Description: Mohacsi, Mate, et al. Evaluation and comparison of methods for neuronal parameter optimization using the Neuroptimus software framework. ''PLoS Comput Biol''. 2024 Dec; '''20''' (12):e1012039
Regulation of sharp wave-ripples by cholecystokinin-expressing interneurons and parvalbumin-expressing basket cells in the hippocampal CA3 region.
Description: Yang, Yuchen, et al. Regulation of sharp wave-ripples by cholecystokinin-expressing interneurons and parvalbumin-expressing basket cells in the hippocampal CA3 region. ''Front Comput Neurosci''. 2025; '''19''': 1591003
A multiscale electro-metabolic model of a rat neocortical circuit reveals the impact of ageing on central cortical layers.
Description: Farina, Sofia, et al. A multiscale electro-metabolic model of a rat neocortical circuit reveals the impact of ageing on central cortical layers. ''PLoS Comput Biol''. 2025 May; '''21''' (5):e1013070
Persistent Adaptation through Dual-Timescale Regulation of Ion Channel Properties.
Description: Mondal, Yugarshi, et al. Persistent Adaptation through Dual-Timescale Regulation of Ion Channel Properties. ''bioRxiv''. 2025 Oct 23;