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  <title>NITRC News Group Forum: introducing-a-longitudinal-dti-analysis-pipeline-with-dti-tk</title>
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  <description>Dear all,

I'm extremely excited to report that DTI-TK now delivers a major new application area:

Unbiased longitudinal DTI analysis.

This new framework is the first to apply our state-of-the-art tensor-based registration to accurately quantify longitudinal changes of tissue microstructure as assessed by DTI.

The framework is reported in our Neuroimage paper (in press):

http://dx.doi.org/10.1016/j.neuroimage.2013.01.044

Our evaluation demonstrates its superior specificity and sensitivity, which can be particular important for detecting early changes in many neurological disorders, such as dementia.

Gary
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